Deep Learning-Based Diagnosis of Temporomandibular Joint Osteoarthritis Using Whole-Body Bone Scans

Published in iScience, 2025

Authors: Yeon-Hee Lee, Hee-Sung Kim, Seonggwang Jeon, Q-Schick Auh, Il Ki Hong, Sunju Choi, Fernando Guastaldi, Hyungsoon Im, Yung-Kyun Noh, Akhilanand Chaurasia

Venue: iScience, 2025

This study developed deep learning models based on the VGG16 architecture to automatically diagnose temporomandibular joint osteoarthritis (TMJ-OA) from bone scintigraphy. Using a dataset of 1,943 patients (3,886 TMJs), the VGG16-Lite model achieved diagnostic accuracy of AUC > 0.90 on head-and-neck imaging across age and sex subgroups, outperforming pretrained models.

My contributions: Manuscript writing, data analysis, data interpretation, and figure preparation.

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